This is our expertise…
Research & Validation
We help you identifying what works for your application and develop customized assays and procedures. Our expertise in validation is key to your success in effect-directed analysis.
Industrialization
We believe that planar effect-directed analysis and bioautographic methods need a high level of standardization. our mission is the prototyping of ready to use planar test kits.
Know-How Transfer
We offer hands-on workshops and training as well as consulting in planar method establishement.
Lab-Services
Our fully equipped service lab and our experts await your samples and analysis requests
Bioautography & Effect-Directed Analysis
Our Technology: planar Bioassays
planar Effect-Directed Analysis p-EDA is the combination of separating multicompound mixtures and assessment of their bioactivity in one method. The reproducibility of the planar chromatographic separation as well as the exclusion of possible artefacts by including suitable controls is key for success of planar bioassays.
planar Yeast Estrogen Screen (pYES)
The reporter gene assay for the human estrogen receptor α in recombinant yeast cells, offers rapid and sensitive detection of endocrine antagonists: it detectd endocrine disruptors in water as well as phytoestrogens in food and herbs.
planar Enzyme Inhibition Assays
Detection of Enzyme Inhibitors are relevant in actives development as well as in toxicological assessment. We offer rapid colorimetric planar enzyme assays for multiplex samples: e.g. Xanthine Oxidase, Acetyl- und Butyryl-Cholin-esterase, α/β-Glucosidase, Lipase. etc.
planar
Antimicrobial & Antifungal Assays
Microbial and fungal cytotoxicity is of mutliple interest in the industry and regulatory bodies.
Contact us for strains of interest.
planar Toxicology
Several microbial and mammalian cell assays for the assessment of toxicological effects in environmental, pharma, food, cosmetic and agro samples are in our pipeline. Contact us for available assays.
Technology Steps in a nutshell
HPTLC Method Development & Services for Quality Control in Pharma, Food & Cosmetics
High Performance Thin Layer Chromatography is the fully automated, precise and highly reproducible form of planar Chromatography. For Identification of pharmaceutical ingredients and complex samples from food, cosmetics, and agronomy we offer method development and analytical services.
LEARN MOREOur Team
Dr.-Ing. Evelyn Wolfram
Head of Development & Production
Dipl.-Biol.
Andreas Schönborn
Head of Research
M.Sc. Sarah Bräm
Head of Lab Services
Dipl-Ing, MBA
Stephan Schilling
Stephan Schilling
CEO, Finances